Cannabinoids affects on Alzheimer’s & Dementia
Enjoy these links to studies and research on cannabis and various medical condition. Supplementation with cannabinoids will have different effects for each person, we are not medically trained or qualified to give medical advice. We do not suggest that cannabis will treat, cure or prevent any particular medical condition, we merely present these links and research to aid your further investigation. The majority of these studies are conducted under strict supervision with high doses.
There are many underlying factors leading to dementia and Alzheimers and many new discoveries being made all the time. CBD and other cannabinoids are showing much promise as a tool to combat these debilitating conditions. As well as having anti-inflammatory, neuro-protective and neurogenesis properties, CBD has been shown to increase blood flow to the brain; all of these factors suggest why CBD may offer real hope to those suffering from these conditions.
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Review of the evidence for cannabinoids in common forms of dementia associated with neurodegeneration: Alzheimer’s disease (AD), vascular dementia (VD), Huntington’s disease (HD), and Parkinson’s disease (PD).
With few therapies for the wide range of neurodegenerative diseases, scientists are still in search of new therapeutic approaches to the problem. Cannabis compound, cannabidiol (CBD), which lacks any unwanted psychotropic effect, may represent a very promising agent with the highest prospect for therapeutic use.
Link: Cannabidiol and Other Cannabinoids Reduce Microglial Activation In Vitro and In Vivo: Relevance to Alzheimer’s Disease
This study compared the effects of CBD with those of other cannabinoids on microglial cell functions in vitro, learning behaviour and cytokine expression after Aβ intraventricular administration to mice.
Link: Cannabidiol Modulates the Expression of Alzheimer’s Disease-Related Genes in Mesenchymal Stem Cells
This study evaluated whether pre-treatment with cannabidiol (CBD), at 5 μM concentration, modulated the transcriptional profile of MSCs derived from gingiva (GMSCs) in order to improve their therapeutic potential, by performing a transcriptomic analysis by the next-generation sequencing (NGS) platform.