Cannabinoids affects on Depression
Enjoy these links to studies and research on cannabis and various medical condition. Supplementation with cannabinoids will have different effects for each person, we are not medically trained or qualified to give medical advice. We do not suggest that cannabis will treat or cure any particular medical condition, we merely present these links and research to aid your further investigation. These studies are conducted under strict supervision with high doses.
There are many possible underlying causes of depression from diet and lifestyle to disease and stress. There are also many things we can do and lifestyle choices we can make to help restore balance and happiness into our lives. Each month we will investigate a medical condition in greater detail so sign up as a NuFriend to get notified of our coming free resources.
Cannabidiol (CBD) – which is non-psychoactive, non-toxic and non-addictive – has been repeatedly observed as a fast-acting antidepressant. Many factors can dampened the functioning of one’s own cannabinoids which help balance the body and mind. CBD can catalyse many reactions within our endocannabinoid system, enabling optimal functioning and causing an increased release of glutamate and serotonin where needed.
LINK: Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects
This study aimed at investigating the potential regulatory capacity of the potent synthetic cannabinoid HU210 on hippocampal neurogenesis and its possible correlation with behavioural change.
LINK: Cannabidiol induces rapid-acting antidepressant-like effects and enhances cortical 5-HT/glutamate neurotransmission: role of 5-HT1A receptors.
Evaluating the effects of CBD following acute and chronic administration in the olfactory bulbectomy mouse model of depression (OBX), and investigating the underlying mechanism.
Examining the properties of CBD using the ‘depressive-like’ Wistar-Kyoto (WKY) rat, focusing on the drug’s effect on anhedonia-like behaviours.
Link: Antidepressant-like and anxiolytic-like effects of cannabidiol: a chemical compound of Cannabis sativa.
This study reviewed studies of animal models using CBD as an anxiolytic-like and antidepressant-like compound.